Prof. Tomás Torroba’s group at the University of Burgos in Spain has synthesized a new series of fluorogenic probes to obtain discrimination between traces of chemical warfare agents (CWA) and their mimics, in water or organic solvent. The new probes were tested against chemical warfare agents by Pär Wästerby´s group at the Swedish Defence Research Agency in Sweden, who also proved the discrimination power using Multivariate Data Analysis. The synthesis of the reported fluorogenic probes is simple and straightforward, and should be relatively simple to adapt in technological applications for in field detection of CWA.
J. Am. Chem. Soc., 2014, 136 (11), pp 4125–4128.
Borja Díaz de Greñu †, Daniel Moreno †,Tomás Torroba *†, Alexander Berg ‡,Johan Gunnars ‡, Tobias Nilsson ‡,Rasmus Nyman ‡, Milton Persson ‡,Johannes Pettersson ‡, Ida Eklind §, andPär Wästerby *§