Xu X, Kim K, Li H, Fan DL.
Adv Mater. 2012 Oct 23;24(40):5457-63.
Materials Science and Engineering Program, Texas Materials Institute, Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
Abstract
Surface enhanced Raman scattering (SERS) is sensitive enough for single-molecule biochemical detection, but it is extremely difficult to obtain a large number of SERS hotspots for sensitive and reproducible detection. It is even more challenging to assemble the hotspots at designated positions for location predictable sensing. Here, we report an original strategy for the synthesis, manipulation, and assembling of plasmonic nanocapsule SERS sensors for high-sensitivity biochemical detection at predictable locations.
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